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Dynamic Light Control of Bispecific Antibody Production

Cologne, November 19, 2025Ningaloo Biosystems has released a new white paper showcasing advances in its proprietary optogenetic platform, now applied to dynamic control of bispecific antibody assembly in mammalian cells.

The study demonstrates how light-inducible expression can guide multi-chain protein assembly, enabling graded control over bispecific antibody formation simply by adjusting illumination. This approach improves product quality, enhances consistency, and simplifies downstream processing, bringing a new level of precision and flexibility to industrial bioproduction.

These results highlight optogenetics as a practical, adaptable tool for next-generation biologics manufacturing, providing a foundation for responsive, high-performing production processes.

Download the whitepaper here:

Guiding Protein Assembly with Light to Improve Product Quality

About Ningaloo
Ningaloo Biosystems is pioneering advancements in biopharmaceutical production by engineering host cells for real-time process control through optogenetics. This approach enables cybergenetic bioprocessing to achieve unprecedented efficiency in manufacturing complex proteins and gene therapeutics, ultimately reducing costs and expanding access to cutting-edge treatments.

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