Cologne, November 19, 2025 — Ningaloo Biosystems has released a new white paper showcasing advances in its proprietary optogenetic platform, now applied to dynamic control of bispecific antibody assembly in mammalian cells.
The study demonstrates how light-inducible expression can guide multi-chain protein assembly, enabling graded control over bispecific antibody formation simply by adjusting illumination. This approach improves product quality, enhances consistency, and simplifies downstream processing, bringing a new level of precision and flexibility to industrial bioproduction.
These results highlight optogenetics as a practical, adaptable tool for next-generation biologics manufacturing, providing a foundation for responsive, high-performing production processes.
Download the whitepaper here:
Guiding Protein Assembly with Light to Improve Product Quality
About Ningaloo
Ningaloo Biosystems is pioneering advancements in biopharmaceutical production by engineering host cells for real-time process control through optogenetics. This approach enables cybergenetic bioprocessing to achieve unprecedented efficiency in manufacturing complex proteins and gene therapeutics, ultimately reducing costs and expanding access to cutting-edge treatments.

