Cologne, December 04, 2025 — A recent review published in the journal npj Systems Biology and Applications, a partner journal of the Nature Portfolio, has cited the collaborative NAR paper developed together with the team of Prof. Dr. Dagmar Wachten in Bonn.
The cited study, published in Nucleic Acids Research, introduces a potent optogenetic system for precise, light-controlled gene expression in mammalian cells. The inclusion of this work in an npj Systems Biology and Applications review underscores the growing relevance of optogenetic strategies within the broader field of dynamic gene regulation and bioproduction.
The review highlights how light-responsive tools can support more flexible and fine-tuned control of cellular processes, reflecting the direction Ningaloo Biosystems is exploring through its optogenetic platform for cyber-bioproduction.
Read the original NAR paper:
https://academic.oup.com/nar/article/53/12/gkaf546/8178389?login=true
Read the npj review:
https://www.nature.com/articles/s41540-025-00621-y
About Ningaloo
Ningaloo Biosystems is pioneering advancements in biopharmaceutical production by engineering host cells for real-time process control through optogenetics. This approach enables cybergenetic bioprocessing to achieve unprecedented efficiency in manufacturing complex proteins and gene therapeutics, ultimately reducing costs and expanding access to cutting-edge treatments.